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This paper describes the design of a programmable microsystem for processing digital audio effects implemented in an FPGA. The microsystem is designed using an application-specific reconfigurable processor, a bank of RAMs, and a graphical user interface based on an LCD touch panel. The processor is designed using 15 audio effects based on delays and dynamic domain and frequency domain processing. The effects are designed using Megafunctions and the Quartus II FIR compiler , simulated in Simulink using DSP Builder, and configured using a user graphic interface. The programmable microsystem is implemented on the DE2-70 development board, and its operation is verified using an MP3 player and a speaker. Additionally, the microsystem allows the generation of effects with high fidelity using a maximum sample rate of 195.62 MSPS and can be embedded into a SoC.